Wagner, Jonathan M.; Christensen, Devin E.; Bhattacharya, Akash; Dawidziak, Daria M.; Roganowicz, Marcin D.; Wan, Yueping; Pumroy, Ruth A.; Demeler, Borries; Ivanov, Dmitri N.; Ganser-Pornillos, Barbie K.; Sundquist, Wesley I.; Pornillos, Owen
(American Society for MicrobiologyArts and ScienceDepartment of Chemistry and BiochemistryUniversity of VirginiaUniversity of UtahUniversity of Texas Health Science Center at San AntonioUniversity of Lethbridgehttps://doi.org/10.1128/JVI.01563-17, 2018)
Restriction factors are intrinsic cellular defense proteins that have evolved to block microbial infections. Retroviruses such as HIV-1 are restricted by TRIM5 proteins, which recognize the viral capsid shell that surrounds, ...