Browsing by Subject "E-site"

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  • The conserved GTPase HflX is a ribosome splitting factor that binds to the E-site of the bacterial ribosome 
    Coatham, Mackenzie L.; Brandon, Harland E.; Fischer, Jeffrey J.; Schummer, Tobias; Wieden, Hans-Joachim (Oxford University PressArts and ScienceDepartment of Chemistry and BiochemistryUniversity of AlbertaUniversity of Lethbridgehttps://doi.org/10.1093/nar/gkv1524, 2016)
    Using a combination of biochemical, structural probing and rapid kinetics techniques we reveal for the first time that the universally conserved translational GTPase (trGTPase) HflX binds to the E-site of the 70S ribosome ...