Browsing Golsteyn, Roy by Title

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Genotoxic anti-cancer agents and their relationship to DNA damage, mitosis, and checkpoint adaptation in proliferating cancer cells

Swift, Lucy H.; Golsteyn, Roy (M D P I A GArts and ScienceDepartment of Biological SciencesUniversity of Lethbridge, 2014)

When a human cell detects damaged DNA, it initiates the DNA damage response (DDR) that permits it to repair the damage and avoid transmitting it to daughter cells. Despite this response, changes to the genome occur and ...
Synthesis, characterization and anticancer activities of cationic η6-p-cymene ruthenium(II) complexes containing phosphine and nitrogenous ligands

Guimaraes, Ivelise D. L.; Marszaukowski, Flávia; Rutka, Priscila B.; Borge, Luis F.; Ribeiro, Renan A. P.; Ricardo de Lazaro, Sergio; Castellen, Patrícia; Sagoe-Wagner, Araba; Golsteyn, Roy M.; Boeré, René T.; Wohnrath, Karen (ElsevierArts and ScienceDepartment of Biological SciencesDepartment of Chemistry and BiochemistryUniversidade Estadual de Ponta GrossaUniversidade do Estado de Minas GeraisInstituto Federal Catarinense, Rua das RosasUniversity of Lethbridgehttps://doi.org/10.1016/j.poly.2022.115980, 2022)

Ruthenium-based anticancer agents have created a center of attention in the field of inorganic medicinal chemistry. The first fully characterized cationic ruthenium(II)-arene complexes [Ru(η6-p-cymene) (PAr3)LNCl]+ with ...

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