Browsing Demeler, Borries by Subject "Antiretroviral"

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  • Yu, Corey H.; Bhattacharya, Akash; Persaud, Mirjana; Taylor, Alexander B.; Wang, Zhonghua; Bulnes-Ramos, Angel; Xu, Joella; Selyutina, Anastasia; Martinez-Lopez, Alicia; Cano, Kristin; Demeler, Borries; Kim, Baek; Hardies, Stephen C.; Diaz-Griffero, Felipe; Ivanov, Dmitri N. (Nature Publishing GroupArts and ScienceDepartment of Chemistry and BiochemistryUT Health San AntonioAlbert Einstein College of MedicineEmory School of MedicineUniversity of LethbridgeUniversity of Montanahttps://doi.org/10.1038/s41467-021-21023-8, 2021)
    SAMHD1 impedes infection of myeloid cells and resting T lymphocytes by retroviruses, and the enzymatic activity of the protein—dephosphorylation of deoxynucleotide triphosphates (dNTPs)—implicates enzymatic dNTP depletion ...